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The ZSC-II® is a simple, self-contained system
for the recovery of high quality progressively motile sperm
from semen. Unlike other conventional sperm preparation
methods, the ZSC technology is fast, inexpensive and simple
one-step standardized method.
The ZSC-II® washes and simultaneously selects the spermatozoa,
thus eliminating the need for the tedious steps of sperm processing
techniques, including dilution and centrifugation. This
product is the answer for the physician who wishes to establish
a self-sufficient practice and eliminate the need for outside
laboratory assistance for semen preparation.
ZSC-II® Slide Presentation
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And
yes... it really is that simple.
The Unique Configuration of the ZSC-II® Technology
The ZSC-II® column maximizes and combines
the "swim-up/swim-down" phenomenon, yielding a greater
number of high-quality, morphologically normal, motile
spermatozoa. Because
the semen specimen is safely protected within the one-of-a-kind
conical cavity inside the ZSC column prior to the addition
of media, the risks of "mixing" the media with the specimen
are eliminated. Thus, the possible contamination of the
media that contains the healthy spermatozoa is totally reduced.
Following
the placement of the seminal specimen into the ZSC conical
cavity, media is placed around and over the cone. During the
incubation period (15 minutes to one hour, depending upon the procedure
to be performed), the most motile and morphologically normal sperm "swim-up" and
out of the cone, and subsequently "swim-down" into the
media surrounding the cone. This process not only separates
the most motile sperm from the seminal plasma, but also
washes the sperm, thus eliminating the need for timely
centrifugation procedures.
The Principle Behind the ZSC Technology
The principle behind the ZSC technology is the unique geometric
configuration of the columns, which includes the conical
cavity inside the ZSC. Furthermore, when the ZSC-II® is used
in conjunction with the SpermPrep Medium (a HEPES buffered,
HAMS F-10 formulation), maximal retrieval (up to 100%)
of morphologically normal, highly motile sperm can be expected. Comparatively,
in conventional swim-up methods, only a portion of media
containing viable sperm is retrievable and could allow
contamination of the inseminate, due to differences in the techniques.
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